One Word Lights a Fuse
I'm infuriated. I'm beyond livid! All because of one word.
One little word.
And if you're a woman who's concerned about bone health, I think you'll be angry too.
We'll start with a recent FDA announcement about bisphosphonate drugs--better known by familiar brand names such as Fosamax, Boniva, Reclast, and Actonel.
I'm sure you're aware that this class of drugs is supposed to strengthen bones in women at risk of osteoporosis. But the fact is, these drugs are actually linked to INCREASED fracture risk.
Nevertheless, after a review of bisphosphonate studies, FDA officials announced that they could find no evidence that the drugs increase risk of fractures to the thighbone (femur) below the hip joint.
Too bad those officials couldn't make it to the annual meeting of the American Academy of Orthopaedic Surgeons in New Orleans earlier this month. Because two different studies presented at that meeting completely contradict the FDA announcement.
Wonderful things
Take 112 post-menopausal women with osteoporosis. Give half of them a bisphosphonate drug. Give the other half daily calcium and vitamin D supplements. Four years later take bone scans of their thighbones. Results: On average, subjects in the drug group had increased buckling ratio compared to non-drug subjects. Higher buckling ratio equals higher risk of fracture.
That's study number one.
In the second study, bone biopsies were taken from 21 post- menopausal women who had broken their femur. Twelve of the women had taken bisphosphonates for an average of more than eight years.
Lead researcher, Dr. Joseph Lane of Weill Cornell Medical College, explained to HealthDay News that normally about 20 percent of a bone is new, about 60 percent is middle-aged, and about 20 percent is old.
In the women taking the drugs, 90 percent of the bone was old.
Dr. Lane added that when too much of the bone is old, microdamage to the bone can't be repaired. Dr. Lane: "What I think is happening is, women keep doing microdamage to the bone."
And there's the word that set me off: women.
Women keep doing microdamage to the bone. Bisphosphonates don't hurt the bone. Women hurt the bone.
Should I cut Dr. Lane some slack? After all, maybe he just carelessly misspoke. Or maybe he was even misquoted. Maybe. But two years ago, Dr. Lane led another similar study that found a very specific type of thighbone fracture that occurred in women who used Fosamax. And here was his comment to HealthDay News in 2008: "This is a great drug that does wonderful things."
Great drug. Fantastic drug! The problem with the drug, obviously, is women. If they would just not take the drug, there would be no fractures!
Speaking of women...when ABC News reported on the bisphosphonate link to femur fracture risk, scores of women went to the ABC website and shared their experiences. Here are just a few of the typical comments from bisphosphonate users:
"...developed aches in my hips, and weakness in the legs..."
"...my femur broke worst pain in the world..."
"...my mother's femur fractured..."
"...had a slight fall and my left femur shattered..."
"...my right leg just gave out and I fell..."
"...had compression fractures of the spine..."
"...fell and broke my right femur bone..."
"...fell to my knees splitting my femur..."
These painful testimonials about this "great drug" go on and on and on.
In one comment, however, a woman breaks the pattern. She notes that it's good to vent in this spontaneous ABC forum, but the next stop for all these women should be the FDA website (fda.gov). There, they can file a formal complaint that will become part of the permanent record of these drugs that are really NOT great at all. Not even close.
Women who want to protect their bones without prescription drugs can find suggestions about key nutrients necessary for optimal bone health in the e-Alert Rags to Riches (1/25/07).
About the author

Jenny Thompson is the Director of the Health Sciences Institute and editor of the HSI e-Alert. Through HSI, she and her team uncover important health information and expose ridiculous health misinformation, most notably through the HSI e-Alert.
Visit www.hsionline.com to sign up for the free HSI e-Alert.
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Comments
jam427
Oh my, Ladies you are a beautiful creation, I know the medical community takes advantage of you and scare you for many unnecessary tests, as they do men with their prostate and you when it comes to mammograms osteoporosis and so on, that does not mean that you should not be on the look out for abnormalities, but be a little more carful when it comes to too many biopsies and the kind of medication prescribed, the same goes for men, take care mi ladies.
Detox Foot Pads
I have to say that if we eat all the necessary nutrients our body needs -- including vitamins, minerals, amino acids, enzymes, etc, we wouldn't have any of these problems (well, let me add that we should also NOT put in all the toxins that most of us do).
I drink raw milk. I eat lots of fruits and veggies. I have never broken a bone in my body. As I approach middle age, I am not afraid of breaking bones.
However, A broken hip bone is what caused the death of my grandma. She was taking one of these medications, I can't remember what one. Along with a myriad of other drugs. She was healthy except the damage the pharmaceuticals were doing to her.
Anonymous
I think what we need is a balanced viewpoint on the pros and cons of prescription drugs. Whilst it is true that there will always be a balance between the beneficial effects of drugs and side effects. What we need to look at is EVIDENCE, unfortunately the reporting on this website is not balanced or evidence based, and many of the people reading this will accept this information at face value. If my mother had osteoperosis i would recommend one of these drugs for her- being mindful of the very rare risk of jaw osteonecrosis. I would recommend a review after 4-5 years due to the long term 'frozen bone' fracture incidence, which is being referred to above. However these drugs DO INCREASE BONE DENSITY AND REDUCE FRACTURES, which are often fatal in the elderly. The reports above are being purposefully misquoted. People should take the drug AND calcium and vit D. Otherwise how will the bone remodel?? I'm all for debate on the use of alternative medications for the treatment of disease, but not when it is biased and misleading. Be informed, but always consider WHO is writing the information and what their agenda is. Ie are they trying to sell you a MIRACLE CURE!!
Alice Wessendorf
Anonymous,
Thank you for your comment. Actually the beauty of HealthierTalk.com is that anyone can join our community, participate in conversations, and publish things from their own viewpoint. It's what we feel makes us a unique website and community.
We have some of the most insightful readers and community members on the Net and we love to hear from them both when they agree with another member's viewpoint as well when they don't. We feel their voices are valid and should be heard. And we certainly don't expect them to take anything at face value and from one single source. Judging from their lively conversations they certainly don’t.
We all have our own stories, our own unique viewpoints, and our own paths. Thank you once again for sharing your viewpoint. You, and your opinions, are welcome here.
Anonymous
I for one am weary with so many test results in favor of Big-Pharma as they turn out to be bogus, many believe that these drugs are miraculous, well good luck, to me the only miracle cure is NATURE and there are natural cures there anywhere from headaches to cancer and these researchers knows this, when our bodies do not absorb enough Vitamin D we run into problems ,mineral that we lack, if we do not have enough stomach acid this is a major factor for out illnesses, maybe, just maybe there is a chance that a certain drug maybe beneficial but I would not risk that on a family member unless there is absolutely and I mean absolutely no other choice, and this a problem with so many drugs the odds are five to one against being beneficial, do not believe me when you hear a commercial about any drug, though they say it so fast about the negatives of such, I am glad they have to mention this, I for one will not run to my Dr to get a prescription. JAM
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